CVR - Coronavirus Vaccines R&D Roadmap

Animal and Human Infection Models for Coronavirus Vaccine Research

Milestones not started
0
Milestones in progress
13
Milestones completed
2
Goals
Strategic goal
4.1

Animal models

Ensure that appropriate animal models are developed and available for conducting R&D for broadly protective coronavirus vaccines.

Milestones
4.1.a

In vitro and organoid models

4.1.b
High priority

Resource availability

4.1.c
High priority
Ongoing

International workshops

4.1.d

DPP4 binding

4.1.e
High priority

Standardization and validation

4.1.f

Transmission dynamics

4.1.g

Vaccine candidate comparisons

4.1.h

Immunobridging

4.1.i

Severe disease

Strategic goal
4.2

Controlled human models

Establish the role of a CHIM in R&D for broadly protective coronavirus vaccines and optimize the model for vaccine research.

Milestones
4.2.a
Ongoing

Human models workshops

4.2.b

Prior exposure

4.2.c
High priority

Standard Operating Procedures

4.2.d
High priority

Principles for licensure

4.2.e
High priority

Standardization

4.2.f

Collaborative networks