CVR - Coronavirus Vaccines R&D Roadmap

Milestone
3.2.f

Adjuvant repository

In progress

Create a repository of available adjuvants that are accessible and available to vaccine R&D researchers globally.

Progress Highlights

NIAID launched the Vaccine Adjuvant Compendium (VAC) in 2021 which aims to provide access to adjuvant metadata for vaccine researchers and developers; currently, the database includes 91 adjuvants, and users have the ability to filter based on keywords, receptor, immune profile induced, pathogen, product grade, and whether a clinical trial has been conducted

Liang 2020 compiled lists of aluminum-based, emulsion, and TLR agonists used as adjuvants in coronavirus vaccine formulations, along with immunologic response and animal models used in preclinical testing.