CVR - Coronavirus Vaccines R&D Roadmap

Milestone
1.2.d

Reagent availability

In progress

Promote availability of reagents, such as reference monoclonal antibodies for antigen characterization, necessary for evaluating priority coronaviruses, which include sarbecoviruses and merbecoviruses. 

Progress Highlights

Máte 2026 developed a universal pan-coronavirus RT-PCR system for detection of pathogenic coronaviruses, which has been successfully tested on both human and animal coronavirus specimens.

Chen 2025 lists critical reagents for detecting novel coronaviruses, determining putative host range, and investigating therapeutic countermeasures.

CDCreativeDiagnosticsSinoBiological, and R&D Systems have repositories of regents used to characterize different animal and human-derived coronaviruses.