CVR - Coronavirus Vaccines R&D Roadmap

Milestone
1.2.g

Metagenomic sequencing methods

In progress

Develop a standardized approach to metagenomic sequencing methodologies, analyses, and data sharing to facilitate  comparability of results. 

Progress Highlights

Eloe-Fadrosh 2024 describe the Genomics Standard Consortium, which maintains the Minimum Information about any (x) Sequence (MIxS) reporting standard for genomic and metagenomic data, abides by the FAIR (Findable, Accessible, Interoperable, and Reusable) principles, and provides ontologies to encourage the use of standardized terms in public data repositories.

Chang 2024 propose “10 recommendations for reporting virome-scale studies” which builds upon the MIxS standards to facilitate comparable and scalable downstream analyses on virus discovery, evolution, and ecology.